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The role and mechanism of SIRT1-mediated ferroptosis in postoperative cognitive dysfunction of aged mice
Medical Journal of Chinese People′s Liberation Army   Vol. 50, Issue 3, Pages: 332-340(2025)
Basic Research | 更新时间:2025-04-18
    • The role and mechanism of SIRT1-mediated ferroptosis in postoperative cognitive dysfunction of aged mice

    • According to the latest research, sevoflurane anesthesia reduces the expression of SIRT1 in the hippocampus of elderly mice, and upregulating SIRT1 can alleviate its induced neuronal death and ferroptosis.
    • DOI:10.11855/j.issn.0577-7402.0526.2024.1025    

      CLC: R749.1
    • Received:19 April 2024

      Accepted:2024-07-13

      Published:28 March 2025

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  • Liu Bao-Lin,Cao Wei-Fu.The role and mechanism of SIRT1-mediated ferroptosis in postoperative cognitive dysfunction of aged mice[J].Medical Journal of Chinese People′s Liberation Army,2025,50(03):332-340. DOI: 10.11855/j.issn.0577-7402.0526.2024.1025.

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Related Author

Liu Bao-Lin
Cui Lin-Yu
Wang Jing-Ya
Duan Jing-Yao
Li Yun-Feng
Dai Wei
Guo Wen-Zhi
Zhou Tian-Tian

Related Institution

Department of Anesthesiology, the Seventh Medical Center of Chinese PLA General Hospital
Academy of Military Medical Sciences, Academy of Military Sciences
Institute of Military Cognitive and Brain Sciences, Academy of Military Medical Sciences, Academy of Military Sciences
College of Anesthesiology, Shanxi Medical University
Department of Traditional Chinese Medicine Rehabilitation, 910th Hospital, Joint Logistics Support Force of Chinese PLA
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