气管食管瘘临床诊疗研究进展
Progress in clinical diagnosis and treatment of tracheoesophageal fistulas
- 解放军医学杂志 2023年48卷第12期 页码：1473-1477
- 作者机构：
1.遵义医科大学人体解剖学教研室，贵州遵义 563003
2.北京市应急总医院呼吸内科，北京 100028
3.秦皇岛市第一医院呼吸与危重症医学科，河北秦皇岛 066000
- 作者简介：
吴彤，医学硕士，主要从事线粒体动力学方面的研究
杨胜波，E-mail：yangshengbo8205486@163.com
- 基金信息：国家自然科学基金(32260217);河北省自然科学基金(H2021107002)
DOI：10.11855/j.issn.0577-7402.0426.2023.0731
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吴彤, 周云芝, 徐淑凤, 等. 气管食管瘘临床诊疗研究进展[J]. 解放军医学杂志, 2023, 48(12): 1473-1477.
Wu Tong,Zhou Yun-Zhi,Xu Shu-Feng,et al.Progress in clinical diagnosis and treatment of tracheoesophageal fistulas[J].Medical Journal of Chinese People′s Liberation Army,2023,48(12):1473-1477.
吴彤, 周云芝, 徐淑凤, 等. 气管食管瘘临床诊疗研究进展[J]. 解放军医学杂志, 2023, 48(12): 1473-1477. DOI： 10.11855/j.issn.0577-7402.0426.2023.0731.
Wu Tong,Zhou Yun-Zhi,Xu Shu-Feng,et al.Progress in clinical diagnosis and treatment of tracheoesophageal fistulas[J].Medical Journal of Chinese People′s Liberation Army,2023,48(12):1473-1477. DOI： 10.11855/j.issn.0577-7402.0426.2023.0731.
摘要
气管食管瘘是指气管或支气管与食管之间的病理性瘘道，包括气管-食管瘘和支气管-食管瘘，临床以气管-食管瘘较多见。气管食管瘘致病原因较多，可引起严重的并发症，影响生活质量，是一种治疗困难、病死率较高的疾病。气管食管瘘目前治疗方式较多，但多数疗效欠佳，对新兴治疗手段的需求迫切。胸腹部 X 线摄影检出鼻胃管滞留是气管食管瘘诊断的金标准，其主要治疗方法包括外科手术治疗、支架置入、局部生物胶水封闭、干细胞治疗等。本文综述近年气管食管瘘诊断与治疗的主要研究进展，旨在为该病的临床诊治提供参考。
Abstract
Tracheoesophageal fistulas (TEF) is a kind of pathological fistula between trachea or bronchus and esophagus, including tracheoesophageal fistula and bronchoesophageal fistula. In clinical practice, tracheoesophageal-fistula is more often seen. There are many pathogenesis of TEF, which could cause serious complications. It is a disease which has serious impact on the quality of life, difficult to treat and high mortality. There are many methods to treat TEF, but the therapeutic effect is poor. There is an urgent need for new treatment methods to TEF. The detection of nasogastric tube retention by chest and abdominal X-ray is the gold standard for diagnosis. The main treatment methods include surgical treatment, stent implantation, local biological glue blocking, stem cell therapy and so on. In order to provide reference for relevant clinical diagnosis and treatment of TEF, this article reviews the main research progress in the diagnosis and treatment of TEF in recent years.
关键词
气管食管瘘支架生物蛋白胶干细胞再生医学
Keywords
tracheoesophageal fistulasstentfibrin gluestem cellregenerative medicine
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