Effect and mechanism of betaine in reversing ABCB1 transporter-mediated multidrug resistance in chemotherapy of prostate cancer
Medical Journal of Chinese People′s Liberation ArmyVol. 50, Issue 2, Pages: 197-206(2025)
Basic Research|更新时间:2025-03-10
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Effect and mechanism of betaine in reversing ABCB1 transporter-mediated multidrug resistance in chemotherapy of prostate cancer
“The latest research has found that betaine downregulates ABCB1 expression through the PI3K/Akt/NF - κ B signaling pathway, reversing chemotherapy resistance in prostate cancer.”
作者机构:
1.宁夏医科大学总医院泌尿外科,宁夏银川 750001
2.巴中市中心医院泌尿外科,四川巴中 636000
3.宁夏医科大学基础医学院,宁夏银川 750001
4.宁夏回族自治区人民医院泌尿外科,宁夏银川 750001
作者简介:
E-mail: nxmuli@foxmail.com
基金信息:
the Natural Science Foundation of Ningxia Hui Autonomous Region(2023AAC03668;2022AAC03506;2022AAC03160)
Li Ya-Jie,Zhang Hang,Nie Li-Hong,et al.Effect and mechanism of betaine in reversing ABCB1 transporter-mediated multidrug resistance in chemotherapy of prostate cancer[J].Medical Journal of Chinese People′s Liberation Army,2025,50(02):197-206.
Li Ya-Jie,Zhang Hang,Nie Li-Hong,et al.Effect and mechanism of betaine in reversing ABCB1 transporter-mediated multidrug resistance in chemotherapy of prostate cancer[J].Medical Journal of Chinese People′s Liberation Army,2025,50(02):197-206. DOI: 10.11855/j.issn.0577-7402.1176.2024.0508.
Effect and mechanism of betaine in reversing ABCB1 transporter-mediated multidrug resistance in chemotherapy of prostate cancer