Mechanism of senegenin in improving lipopolysacchride-induced inflammatory response of BV2 microglial cell

Mu Bing-Tao; Guo Min-Fang; Yu Jing-Wen; Cao Jia-Lei; Yang Feng-Jun; Jia Si-Wei; Su Qing; Meng Tao; Ma Cun-Gen; Yu Jie-Zhong; Song Li-Juan

doi:10.11855/j.issn.0577-7402.0199.2024.0906

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Mechanism of senegenin in improving lipopolysacchride-induced inflammatory response of BV2 microglial cell

Medical Journal of Chinese People′s Liberation Army Vol. 50, Issue 2, Pages: 188-196(2025)

Basic Research | 更新时间：2025-03-10

- Mechanism of senegenin in improving lipopolysacchride-induced inflammatory response of BV2 microglial cell
- “The latest research has found that Far Star Saponin alleviates inflammation in mouse microglia through the Nrf2/NLRP3 pathway, with an effect comparable to MCC950, providing a new strategy for the treatment of neuroinflammation.”
- 作者机构：
  
  1.山西大同大学脑科学研究所/分子细胞免疫学大同市重点实验室，山西大同 037009
  2.山西大同大学医学院，山西大同 037009
  3.山西中医药大学国家中医药管理局多发性硬化益气活血重点研究室/神经生物学研究中心，山西晋中 030619
  4.大同市第五人民医院神经内科，山西大同 037009
- 作者简介：
  
  Yu Jie-Zhong, E-mail: sxdtyjz@qq.com
  Song Li-Juan, E-mail: slj_0354@126.com
- 基金信息：
  
  the National Natural Science Foundation of China(82004028);the Project of Key Research Laboratory of Traditional Chinese Medicine of Shanxi Province(zyyyjs2024027);the "Four Batches" Science and Technology Innovation Plan Project of Shanxi Province(2022XM33);the Chinese Medicine Scientific Research Project Establishment Plan of Shanxi Provincial Health Commission(2022ZYYC090);the Traditional Chinese Medicine Research Project of Shanxi Province(2023ZYYB2042)
- DOI：10.11855/j.issn.0577-7402.0199.2024.0906
  CLC： R742;R285.5
- Received：20 February 2024，
  
  Accepted：2024-04-12，
  
  Published Online：06 September 2024，
  
  Published：28 February 2025
- 稿件说明：
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穆秉桃, 郭敏芳, 于婧文, 等. 远志皂苷元缓解脂多糖诱导的小鼠小胶质细胞炎症反应的机制[J]. 解放军医学杂志, 2025, 50(2): 188-196.

Mu Bing-Tao,Guo Min-Fang,Yu Jing-Wen,et al.Mechanism of senegenin in improving lipopolysacchride-induced inflammatory response of BV2 microglial cell[J].Medical Journal of Chinese People′s Liberation Army,2025,50(02):188-196.
穆秉桃, 郭敏芳, 于婧文, 等. 远志皂苷元缓解脂多糖诱导的小鼠小胶质细胞炎症反应的机制[J]. 解放军医学杂志, 2025, 50(2): 188-196. DOI： 10.11855/j.issn.0577-7402.0199.2024.0906.

Mu Bing-Tao,Guo Min-Fang,Yu Jing-Wen,et al.Mechanism of senegenin in improving lipopolysacchride-induced inflammatory response of BV2 microglial cell[J].Medical Journal of Chinese People′s Liberation Army,2025,50(02):188-196. DOI： 10.11855/j.issn.0577-7402.0199.2024.0906.

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Mechanism of senegenin in improving lipopolysacchride-induced inflammatory response of BV2 microglial cell

DOI：10.11855/j.issn.0577-7402.0199.2024.0906