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Expression, prognostic relevance of P4HB in glioblastoma and its biological effects on tumor cells
Basic Research | 更新时间:2024-05-13
    • Expression, prognostic relevance of P4HB in glioblastoma and its biological effects on tumor cells

    • 最新科技播报,科研人员深入探索了脯氨酸4-羟化酶β多肽(P4HB)在多形性胶质母细胞瘤(GBM)中的作用。研究揭示了P4HB在GBM组织中的高表达现象,并发现其高表达与患者不良预后紧密相关。实验结果显示,通过敲除P4HB,可有效抑制GBM细胞的增殖和迁移能力。这一发现为GBM的预测标志物和潜在治疗靶点提供了新的线索,为未来的临床治疗提供了新的思路。
    • Medical Journal of Chinese People′s Liberation Army   Vol. 49, Issue 4, Pages: 459-467(2024)
    • DOI:10.11855/j.issn.0577-7402.2540.2023.1012    

      CLC: R742.5;R285
    • Published:28 April 2024

      Published Online:12 October 2023

      Received:06 December 2022

      Accepted:07 April 2023

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  • Huang Guan-You,Hou Xiao-Hong,Ge Xue-Cheng,et al.Expression, prognostic relevance of P4HB in glioblastoma and its biological effects on tumor cells[J].Medical Journal of Chinese People′s Liberation Army,2024,49(04):459-467. DOI: 10.11855/j.issn.0577-7402.2540.2023.1012.

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