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Effect and mechanism of proteasome inhibitor MG132 on memory impairment caused by chronic hypoxia in mice
Basic Research | 更新时间：2024-05-13
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    • Effect and mechanism of proteasome inhibitor MG132 on memory impairment caused by chronic hypoxia in mice

    • “科技新闻播报：最新研究揭示了蛋白酶体抑制剂MG132在改善慢性缺氧导致的小鼠记忆损伤方面的潜力。科学家们通过建立缺氧模型，探索了MG132对多巴胺能神经元的影响，发现它能有效抑制Ub-K48和Ub-K63的表达，同时上调TH表达，从而改善记忆功能。这项研究为治疗慢性缺氧引起的记忆损伤提供了新的可能性。”
      ”
    • Medical Journal of Chinese People′s Liberation Army   Vol. 49, Issue 4, Pages: 449-458(2024)

    • DOI：10.11855/j.issn.0577-7402.0569.2023.1012    

      CLC： R742;R965

    • Published：28 April 2024，

      Published Online：12 October 2023，

      Received：19 April 2023，

      Accepted：04 July 2023

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  • Dong Hua-Ping,Li Peng,Li Xiao-Xu,et al.Effect and mechanism of proteasome inhibitor MG132 on memory impairment caused by chronic hypoxia in mice[J].Medical Journal of Chinese People′s Liberation Army,2024,49(04):449-458. DOI： 10.11855/j.issn.0577-7402.0569.2023.1012.

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