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Effects of advanced maternal age on hippocampal synaptic pruning in offspring rats
Medical Journal of Chinese People′s Liberation Army   Vol. 50, Issue 5, Pages: 575-580(2025)
Basic Research | 更新时间：2026-01-28

    • Effects of advanced maternal age on hippocampal synaptic pruning in offspring rats

    • “The latest research has found that synaptic pruning in the hippocampus of older pregnant offspring is abnormal after birth, manifested by reduced dendritic complexity, decreased dendritic spine density, and disordered morphology, which may be one of the mechanisms of brain dysfunction in older pregnant offspring.”

    • DOI：10.11855/j.issn.0577-7402.0804.2025.0218    

      CLC： R742;R714.1

    • Received：07 June 2024，

      Accepted：31 July 2024，

      Published Online：18 February 2025，

      Published：28 May 2025

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  • Jiang Chun-Xue,Han Zi-Yao,Yan Xin-Ru,et al.Effects of advanced maternal age on hippocampal synaptic pruning in offspring rats[J].Medical Journal of Chinese People′s Liberation Army,2025,50(05):575-580. DOI： 10.11855/j.issn.0577-7402.0804.2025.0218.

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