Protective effects of paeonol on human neuroblastoma cells in Parkinson's disease model and its underlying mechanism
Medical Journal of Chinese People′s Liberation ArmyVol. 50, Issue 1, Pages: 69-75(2025)
Basic Research|更新时间:2025-01-23
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Protective effects of paeonol on human neuroblastoma cells in Parkinson's disease model and its underlying mechanism
“The latest research has found that paeonol can alleviate neuronal damage induced by A53T - α - Syn mutation by activating the autophagy pathway to clear overexpressed α - Syn protein. The mechanism may be related to upregulating the JNK/Bcl-2 mediated autophagy pathway.”
作者机构:
1.山西中医药大学多发性硬化益气活血重点研究室/神经生物学研究中心,山西晋中 030619
2.山西医科大学基础医学院生物化学与分子生物学教研室,山西太原 030001
3.山西中医药大学第一临床学院,山西太原 030024
4.山西中医药大学第二临床学院,山西太原 030012
作者简介:
Fan Hui-Jie, E-mail: fanhuijie.happy@163.com
Chai Zhi, E-mail: chaizhi008@126.com
基金信息:
the National Young Qihuang Scholars Training Program (〔2022〕256), the Key National Science and Technology Cooperation Project of Shanxi Province(国中医药人教函(2022)256号);the Outstanding Youth Talents Program of Shanxi Province [〔2019〕35], the Research Project of Shanxi Scholarship Council(202204041101002);the Outstanding Youth Talents Program of Shanxi Province;the Research Project of Shanxi Scholarship Council of China(2021-142)
SUN SHENG-NAN, HE LU-LU, QIN SHAO-CHEN, et al. Protective effects of paeonol on human neuroblastoma cells in Parkinson's disease model and its underlying mechanism. [J]. Medical journal of chinese people′s liberation army, 2025, 50(1): 69-75.
DOI:
SUN SHENG-NAN, HE LU-LU, QIN SHAO-CHEN, et al. Protective effects of paeonol on human neuroblastoma cells in Parkinson's disease model and its underlying mechanism. [J]. Medical journal of chinese people′s liberation army, 2025, 50(1): 69-75. DOI: 10.11855/j.issn.0577-7402.0483.2024.0716.
Protective effects of paeonol on human neuroblastoma cells in Parkinson's disease model and its underlying mechanism