Improvement effect of TSPO ligand YL-IPA08 on lipopolysaccharide-induced depressive and anxiety-like behavior in mice and its anti-inflammatory mechanism
Medical Journal of Chinese People′s Liberation ArmyVol. 49, Issue 12, Pages: 1417-1425(2024)
Basic Research|更新时间:2025-01-08
|
分享给微信好友或者朋友圈
导出参考文献
Improvement effect of TSPO ligand YL-IPA08 on lipopolysaccharide-induced depressive and anxiety-like behavior in mice and its anti-inflammatory mechanism
“The latest research has found that YL-IPA08 can effectively alleviate LPS induced depression, anxiety, and cognitive impairment in mice, possibly by improving neuroinflammation and regulating the TGF - β/Smad pathway.”
作者机构:
1.山西医科大学麻醉学院,山西太原 030001
2.军事科学院军事医学研究院军事认知与脑科学研究所,北京 100850
3.军事科学院军事医学研究院,北京 100850
4.解放军总医院第七医学中心麻醉科,北京 100010
作者简介:
Dai Wei, E-mail: twotou3@126.com
Guo Wen-Zhi, E-mail: elite2005gg@163.com
基金信息:
the National Natural Science Foundation of China(82204358)
Cui Lin-Yu,Wang Jing-Ya,Duan Jing-Yao,et al.Improvement effect of TSPO ligand YL-IPA08 on lipopolysaccharide-induced depressive and anxiety-like behavior in mice and its anti-inflammatory mechanism[J].Medical Journal of Chinese People′s Liberation Army,2024,49(12):1417-1425.
Cui Lin-Yu,Wang Jing-Ya,Duan Jing-Yao,et al.Improvement effect of TSPO ligand YL-IPA08 on lipopolysaccharide-induced depressive and anxiety-like behavior in mice and its anti-inflammatory mechanism[J].Medical Journal of Chinese People′s Liberation Army,2024,49(12):1417-1425. DOI: 10.11855/j.issn.0577-7402.0458.2024.0830.
Improvement effect of TSPO ligand YL-IPA08 on lipopolysaccharide-induced depressive and anxiety-like behavior in mice and its anti-inflammatory mechanism