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Improvement effect of TSPO ligand YL-IPA08 on lipopolysaccharide-induced depressive and anxiety-like behavior in mice and its anti-inflammatory mechanism
Medical Journal of Chinese People′s Liberation Army   Vol. 49, Issue 12, Pages: 1417-1425(2024)
Basic Research | 更新时间:2025-01-08
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    • Improvement effect of TSPO ligand YL-IPA08 on lipopolysaccharide-induced depressive and anxiety-like behavior in mice and its anti-inflammatory mechanism

    • The latest research has found that YL-IPA08 can effectively alleviate LPS induced depression, anxiety, and cognitive impairment in mice, possibly by improving neuroinflammation and regulating the TGF - β/Smad pathway.
    • DOI:10.11855/j.issn.0577-7402.0458.2024.0830    

      CLC: R749.4
    • Published:28 December 2024

      Published Online:30 August 2024

      Received:09 April 2024

      Accepted:2024-05-27

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  • Cui Lin-Yu,Wang Jing-Ya,Duan Jing-Yao,et al.Improvement effect of TSPO ligand YL-IPA08 on lipopolysaccharide-induced depressive and anxiety-like behavior in mice and its anti-inflammatory mechanism[J].Medical Journal of Chinese People′s Liberation Army,2024,49(12):1417-1425. DOI: 10.11855/j.issn.0577-7402.0458.2024.0830.

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